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YearIMPACT-FACTOR
2022  1,200
2021  1,540
2020  1,374
2019  1,023
2018  0,932
2017  0,977
2016  0,799
2015  0,662
2014  0,740
2013  0,739
2012  0,637
2011  0,658
2010  0,654
2009  0,570
2008  0,849
2007  0,805
2006  0,330
2005  0,435
2004  0,623
2003  0,567
2002  0,641
2001  0,490
2000  0,477
1999  0,762
1998  0,785
1997  0,507
1996  0,518
1995  0,502
Vol 43(2009) N 6 p. 982-989;
N.V. Soshnikova1, N.I. Vorobyeva1, A.N. Krasnov1,2, S.G. Georgieva1,3, E.N. Nabirochkina1, Yu.V. Shidlovskii1,2

Novel complex formed by the SAYP transcriptional coactivator

1Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia
2Center of Medical Studies, University of Oslo, Moscow, 119334, Russia
3Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia

Received - 2009-04-27; Accepted - 2009-05-13

A multisubunit complex that contains the novel evolutionarily conserved transcription factor SAYP was isolated, and its protein composition was determined. SAYP was found to unite two complexes with different functions in transcription activation, namely, the chromatin-remodeling complex PBAP (SWI/SNF) and the general transcription factor TFIID, which is the main component of the RNA polymerase II preinitiation complex. The new supercomplex contained the total set of PBAP and TFIID subunits. All components of the supercomplex (SAYP, TFIID, and PBAP) are essential for its effective interaction with the promoters of SAYP dependent genes.

transcription factors, activation of transcription, promoter, chromatin-remodeling complexes, chromatin immunoprecipitation, eukaryotes



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