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Vol 53(2019) N 4 p. 560-570; DOI 10.1134/S002689331904006X Full Text

I.V. Kornienko1,2*, T.G. Faleeva2,3, N.V. Oreshkova4,5,6, S.E. Grigoriev7, L.V. Grigorieva8, Yu.A. Putintseva5, K.V. Krutovsky5,9,10,11

Structural and Functional Organization of the Mitochondrial DNA Control Region in the Woolly Mammoth (Mammuthus primigenius)

1Southern Scientific Centre, Russian Academy of Sciences, Rostov-on-Don, 344006 Russia
2Ivanovsky Academy of Biology and Biotechnology, Southern Federal University, Rostov-on-Don, 344090 Russia
3Branch No. 2 of the 111th Main State Center of Medical Forensic and Criminalistic Examinations, Ministry of Defense of the Russian Federation, Rostov-on-Don, 344000 Russia
4Sukachev Institute of Forest, Siberian Branch, Russian Academy of Sciences, Krasnoyarsk, 660036 Russia
5Genome Research and Education Center, Siberian Federal University, Krasnoyarsk, 660036 Russia
6Laboratory of Genomic Research and Biotechnology, Federal Research Center Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences, Krasnoyarsk, 660036 Russia
7Lazarev Mammoth Museum, Institute of Applied Ecology of the North, North-Eastern Federal University, Yakutsk, 677980 Russia
8International Common Use Center Molecular Paleontology, North-Eastern Federal University, Yakutsk, 677980 Russia
9Department of Forest Genetics and Forest Tree Breeding, Georg-August University of Gottingen, Gottingen, 37077 Germany
10Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991 Russia
11Department of Ecosystem Science and Management, Texas A&M University, College Station, TX 77843-2138 United States

*ikornienko@yandex.ru
Received - 2019-02-07; Revised - 2019-03-04; Accepted - 2019-03-13

The woolly mammoth mitochondrial genome (including the Malolyakhovsky mammoth) has been previously sequenced, followed by the annotation of all its genes (MF770243). In this study, based on the Malolyakhovsky mammoth, we describe for the first time the sites of functional significance in the control region of the woolly mammoth mitogenome.

ancient DNA, mitochondrial DNA, control region, woolly mammoth, paleogenetics



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