Journal of Molecular Biology

Year	IMPACT-FACTOR
2022	1,200
2021	1,540
2020	1,374
2019	1,023
2018	0,932
2017	0,977
2016	0,799
2015	0,662
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2010	0,654
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2006	0,330
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2004	0,623
2003	0,567
2002	0,641
2001	0,490
2000	0,477
1999	0,762
1998	0,785
1997	0,507
1996	0,518
1995	0,502

Vol 44(2010) N 5 p. 769-775;

N.E. Vorob'eva¹*, N.V. Soshnikova¹, Yu.V. Nikolenko¹, Yu.L. Kuz'mina¹, E.N. Nabirochkina¹, S.G. Georgieva^1,2, Yu.V. Shidlovskii^1,3

A Novel Conserved Domain of SAYP Coactivator Mediates the Interaction of TFIID and Brahma Transcription Complexes
¹Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334 Russia
²Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia
³Centre for Medical Studies at Moscow, Moscow, 119334 Russia

^*nvorobyova@gmail.com
Received - 2009-12-25; Accepted - 2010-03-10

Using the S2 cell system of Drosophila melanogaster, it was shown that the key protein domain mediating the interaction of TFIID and Brahma transcriptional complexes within the BTFly supercomplex is the evolutionary conserved SAY domain of SAYP. TFIID and Brahma coactivators participated in the reporter gene activation induced by the SAY domain in cellular nuclei. The components of TFIID and Brahma directly interacting with SAY were identified.

transcriptional factor, activation of transcription, promoter, chromatin remodeling complex, coprecipitation, eukaryotes