Journal of Molecular Biology

Year	IMPACT-FACTOR
2022	1,200
2021	1,540
2020	1,374
2019	1,023
2018	0,932
2017	0,977
2016	0,799
2015	0,662
2014	0,740
2013	0,739
2012	0,637
2011	0,658
2010	0,654
2009	0,570
2008	0,849
2007	0,805
2006	0,330
2005	0,435
2004	0,623
2003	0,567
2002	0,641
2001	0,490
2000	0,477
1999	0,762
1998	0,785
1997	0,507
1996	0,518
1995	0,502

Vol 46(2012) N 1 p. 47-57;

D.A. Ghilarov¹, I.S. Shkundina^1,2*

DNA Topoisomerases and Their Functions in a Cell
¹Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334 Russia
²Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182 Russia

^*irina_shkundina@mail.ru
Received - 2011-07-04; Accepted - 2011-08-04

DNA-topoisomerases are sophisticated enzymes that control the DNA topology in a cell. A wealth of new data concerning the structure and functions of topoisomerases was published recently. The review discusses the basic features of different types of topoisomerases with respect to the catalytic mechanism and focuses on the involvement of topoisomerases in various DNA-related cell processes, such as replication, transcription, recombination, chromatin condensation, and daughter chromatid partitioning.

DNA topoisomerases, structure, function, transcription, replication, chromatin, prokaryotes, eukaryotes